NABP NAPLEX North American Pharmacist Licensure Examination Exam Practice Test

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Total 155 questions
Question 1

A 49-year-old's blood test results have come back from the lab. Their chloride level currently measures 99 mEq/L. How should you interpret this result?



Answer : C

Serum chloride levels should ideally fall between 96-106 mEq/L. For this reason, the patient's chloride level has come back as normal.


Question 2

Which of these drugs is used to promote fetal lung maturation?



Answer : A

Dexamethasone is used to promote fetal lung maturation. This may be necessary in cases of women who need to deliver prematurely. A tocolytic drug, such as nifedipine, may be used to suppress labor whilst dexamethasone works to accelerate fetal lung development.


Question 3

MT is 47-year-old man who presents to the ER with painful, red, swollen area on his left leg. His temperature is 38.4, respiratory rate 30 and heart rate 95. He has been taking cephalexin day 4 today, as prescribed by his primary care physician. His CMP is normal a CBC shows elevated WBC of 16,000/mm3.

What would be the most appropriate antibiotic/s to initiate on MT empirically?



Answer : A

This patient is displaying signs of a severe case of cellulitis. Severe cellulitis is defined as having one of the following: failed oral antibiotic treatment, immunocompromised, clinical signs of deeper infection, or meeting the SIRS criteria. Based on this patient's presentation they have failed antibiotic treatment and meet SIRS criteria. For severe cellulitis, IDSA SSTI guidelines recommend using Vancomycin along with Zosyn.


https://academic.oup.com/cid/article/59/2/e10/2895845/Practice-Guidelines-for-the-Diagnosis-and

Question 4

An order is received to start Milrinone at 0.75mcg/kg/min, Milrinone comes as 20mg/100ml D5W. What is the infusion rate in mL/hr? Patient weighs 115kg.



Answer : C

Patient dose: 0.75mcg 115kg = 86.25mcg/min (100mL/20mg) (86.25mcg/1hr) (60min/1hr) (1mg/1000mcg) = 25.875mL/hr Rate of infusion of Milrinone


Question 5

Which of the following would be most appropriate to treat stenotrophomonas maltophilia?



Answer : D

Primary treatment for stenotrophomonas maltophilia is SMX-TMP. Meropenem, ciprofloxacin, and vancomycin have no coverage.


Question 6

Which of the following side effects should LT be made aware of while on Divalproex Sodium?



Answer : C

Common GI side effects of Valproic Acid and Divalproex Sodium are Weight gain, Nausea, Vomiting, Diarrhea, abdominal pain, dyspepsia. Divalproex sodium or valproic acid affects reproductive endocrine function in women. Menstrual irregularities defined as amenorrhea, oligomenorrhea, and prolonged cycles were common. Gynecomastia is not a side effect of Divalproex Sodium. For list of drugs that causes gynecomastia refer the reference. Gingival hyperplasia is a well-known side effect of phenytoin.


http://www.pharmaco-vigilance.eu/content/drug-induced-gynecomastia

Question 7

Which of the following Anti-epileptic medication can cause pancreatitis?



Answer : C

Cases of life-threatening pancreatitis have been reported in both pediatric and adult patients receiving valproic acid or its analogs. Patients should be warned that abdominal pain, nausea, vomiting, and/or anorexia can be symptoms of pancreatitis that require prompt medical evaluation. If pancreatitis is diagnosed, valproate should be discontinued.


http://www.clinicalpharmacology-ip.com/Forms/Monograph/monograph.aspx?cpnum=637&sec=moncontr&t=0

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Total 155 questions